HEXOKINASE 2 DEPLETION CONFERS SENSITIZATION TO METFORMIN AND INHIBITS GLYCOLYSIS IN LUNG SQUAMOUS CELL CARCINOMA

Hexokinase 2 Depletion Confers Sensitization to Metformin and Inhibits Glycolysis in Lung Squamous Cell Carcinoma

Lung squamous cell carcinomas (SCCs) are highly aggressive tumors, and there is currently no effective targeted therapy owing hindirochakkahaniya.com to the lack of specific mutation targets.Compared with lung adenocarcinoma (ADCs), lung SCCs reportedly utilized higher levels of glucose metabolism to meet the anabolic and catabolic needs required t

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The sweet trade revived

[First paragraph] Women Pirates and the Politics of the Jolly Roger.ULRIKE KLAUSMANN, MARION MEINZERIN & GABRIEL KUHN.New York: Black Rose Books, 1997.x + 280 pp.(Paper US$ 23.99) Pirates! Brigands, Buccaneers, and Privateers in Fact, Fiction, and Legend.JAN ROGOZINSKI.New York: Da Capo Press, 1996.xvi + 398 pp.(Paper US$ 19.95)

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Steroid signaling within Drosophila ovarian epithelial cells sex-specifically modulates early germ cell development and meiotic entry.

Drosophila adult females but not males contain high levels of the steroid hormone ecdysone, however, the roles played by steroid signaling during Drosophila gametogenesis remain poorly understood.Drosophila germ cells in both sexes initially follow a similar pathway.After germline stem cells are established, their daughters form interconnected cyst

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